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At MS Build 2022 the Azure Stack HCI Single Node Cluster Announcement has been done.

Azure Stack HCI running on a single-node cluster behaves very similarly to Azure Stack HCI on a multi-node cluster: it brings native Azure Arc integration, you can add servers to scale out the cluster, and it includes the same Azure benefits. It also supports the same workloads, such as Azure Virtual Desktop (AVD) and Azure Kubernetes Service (AKS) on Azure Stack HCI, and lastly it is supported and billed the same way. To learn more, see Using Azure Stack HCI on a single server.

At this time you cannot install a single cluster with Windows Admin Center.

Therefore, I have collected the Powershell scripts for the deployment on my Github page.

You can find my Github page here: Github/chtwilfer

Comparing singel-node and multi-node clusters

The following table compares attributes of a single-node cluster to multi-node clusters.

Attributes Single-Node Multi-Node
Full software-defined data center (SDDC) stack (hypervisor, storage, networking) Yes Yes
Storage Spaces Direct support Yes Yes
Software Defined Networking (SDN) support Yes Yes
Native Azure Arc integration Yes Yes
Managed through Windows Admin Center and Azure portal Yes Yes
Azure billing/registration Yes Yes
Charged per physical core Yes Yes
Support through Azure Yes Yes
Connectivity (intermittent or connected) Yes Yes
Azure benefits on Azure Stack HCI Yes Yes
Activate Windows Server Subscriptions Yes Yes
Azure Defender and Secured-core Yes Yes
Azure Kubernetes Service on Azure Stack HCI (AKS-HCI) Yes Yes
Azure Virtual Desktop Yes Yes
Azure Site Recovery Yes Yes
Azure Stack HCI: Stretch cluster support No Yes
Use Graphics Processing Units (GPUs) with clustered VMs Yes Yes

Please feel free to comment or come back to me with your thoughts. :-)